Duodenal biopsies for the diagnosis of coeliac disease: are we adhering to current guidance? Open Access.

Abstract: Background The British Society of Gastroenterology guidelines recommend taking at least four duodenal biopsy specimens at the time of upper gastrointestinal (UGI) endoscopy if coeliac disease (CD) is suspected and it has been shown to increase the diagnostic yield of CD. We assessed the compliance to these guidelines within our institution. We then appliedSigueSigue leyendo «Duodenal biopsies for the diagnosis of coeliac disease: are we adhering to current guidance? Open Access.»

New horizon in breast cancer therapy: highlights from the European Society for Medical Oncology. Open Access.

Abstract: This podcast presents an overview of new therapies on the horizon for breast cancer in terms of data presented at the European Society for Medical Oncology Congress, American Society of Clinical Oncology and the San Antonio Breast Cancer Symposium. In the adjuvant setting, results from the Microarray In Node negative Disease may Avoid ChemoTherapy (MINDACT) trial,SigueSigue leyendo «New horizon in breast cancer therapy: highlights from the European Society for Medical Oncology. Open Access.»

Atopic eczema treatment now and in the future: Targeting the skin barrier and key immune mechanisms in human skin.

Abstract: The skin facilitates a number of key roles but its functioning can be impaired by disease. Atopic eczema is a chronic inflammatory disease where the skin barrier has become leaky, and inflammation occurs. It affects up to 20% of children and 3% of adults worldwide, manifesting as red itchy patches of skin with varyingSigueSigue leyendo «Atopic eczema treatment now and in the future: Targeting the skin barrier and key immune mechanisms in human skin.»

Heterogeneity of colon cancer: from bench to bedside. Open Access.

Abstract. The large bowel shows biomolecular, anatomical and bacterial changes that proceed from the proximal to the distal tract. These changes account for the different behaviour of colon cancers arising from the diverse sides of the colon–rectum as well as for the sensitivity to the therapy, including immunotherapy. The gut microbiota plays an important roleSigueSigue leyendo «Heterogeneity of colon cancer: from bench to bedside. Open Access.»